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Retrieves pathway or transcription factor target networks from decoupleR (Progeny, DoRothEA, or CollecTRI).

Usage

get_decoupleR_reference(
  method = "progeny",
  organism = "human",
  n_genes = 500,
  confidence = NULL,
  ...
)

Arguments

method

Reference to retrieve: "progeny", "dorothea", or "collectri".

organism

Target organism (e.g., "human" or "mouse").

n_genes

Number of top genes for Progeny (only used with "progeny").

confidence

Confidence levels (A-E) to filter DoRothEA targets (only used with "dorothea").

...

Additional parameters passed to decoupleR.

Value

A data frame containing the requested reference.