Calculates the signature model with MOMF

build_model_momf(
  single_cell_object,
  cell_type_annotations,
  bulk_gene_expression,
  ...
)

Arguments

single_cell_object

A matrix with the single-cell data. Rows are genes, columns are samples. Row and column names need to be set.

cell_type_annotations

A vector of the cell type annotations. Has to be in the same order as the samples in single_cell_object.

bulk_gene_expression

A matrix of bulk data. Rows are genes, columns are samples. Row and column names need to be set.

...

Additional arguments, silently ignored. Allows extra parameters to pass through the deconvolute() dispatcher without error.

Value

The signature matrix. Rows are genes, columns are cell types.