Usage
deconvolute(
methyl_set,
method = deconvolution_methods,
normalize_results = FALSE,
...
)
Arguments
- methyl_set
A minfi MethylSet
- method
A string specifying the method. Supported methods are 'epidish', 'flowsorted', 'methylcc', 'methylresolver'
- normalize_results
Whether the deconvolution results should be normalized.
Negative values will be put to 0, and the estimates will be normalized to sum to 1.
Defaults to FALSE.
- ...
Additional parameters, passed to the algorithm used. See individual method documentations for details.
Value
A matrix with the probabilities of each cell-type for each individual. Rows are
individuals, columns are cell types.
Examples
ex_data <- minfiData::MsetEx
#> Error in loadNamespace(x): there is no package called ‘minfiData’
result <- deconvolute(ex_data, method='epidish')
#> Loading required package: EpiDISH
#> Error in eval(expr, envir, enclos): object 'ex_data' not found